POLE OMEGA 3 Fish and omega-3 fatty acids. If you keep up with the latest nutrition news, you may have a pretty good sense of what they offer. But, if you’re like many people, you still can’t tell your omega-3s from your omega-6s — and you sure as heck can’t pronounce eicosapentaenoic acid. That’s OK. Our fishing expedition turned up some interesting facts to share about omega-3 fatty acids and fish.